An Insight to Aging

What is aging?

Aging is a phenomenon related to a series of catabolic processes resulting in decreased function and structural integrity of several physiological systems. This process is correlated with a decrease in growth hormone secretion, leading to decreased plasma levels of insulin-like growth factor-1.

What is the growth hormone?

It is a naturally occurring hormone secreted by the pituitary gland which carries out several functions such as turnover of muscle, bone, and collagen, to the regulation of selective aspects of metabolic function, including increased fat metabolism and the maintenance of a healthier body composition in later life. Secretion of growth hormone is reduced a person age leading to disturbed sleep cycles and have negative effects on their memory. So, growth hormone substitution can lead to improved cognitive functioning.

What is human growth hormone (HGH) replacement therapy?

HGH replacement therapy is used in individuals suffering from HGH deficit and is not usually used for healthy individuals or age related decline of HGH and IGF-1. They are also used as a performance-enhancing agents, to increase muscle mass and exercise endurance. However, it is not safe due to its potential side effects such as carcinogenic activity.